Study of resistance to cephalosporin compounds in Salmonella spp. and Salmonella Typhimurium isolated from turkeys

Keyvan Samadi; Mohammad Jahantigh; Reza Esmaeelzadeh Dizaji; Dariush Saadati

doi:10.61838/kman.jpsad.2.1.4

Authors

Keyvan Samadi DVM graduated, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran Author https://orcid.org/0000-0002-0190-8497
Mohammad Jahantigh Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran Author https://orcid.org/0000-0002-6451-9544
Reza Esmaeelzadeh Dizaji Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Author https://orcid.org/0000-0001-9044-1659
Dariush Saadati Department of Food Hygiene, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran Author https://orcid.org/0000-0001-9002-1507

DOI:

https://doi.org/10.61838/kman.jpsad.2.1.4

Abstract

The high consumption of antimicrobial agents in livestock is a global problem that can increase the antibiotic resistance of human and animal bacteria such as Salmonella serotypes. In this study, cloacal swab was used to isolate Salmonella spp. from turkeys in Zabol, Iran. The isolated bacteria were evaluated by polymerase chain reaction to confirm the bacteria and to identify some resistance genes. Disk diffusion test on Mueller-Hinton agar was used to determine the susceptibility of the isolated bacteria to cephalosporin compounds. A total of 33 Salmonella spp. including 19 Salmonella Typhimurium were identified by polymerase chain reaction. Multiple drug resistance (MDR) to cephalosporin compound was observed in Salmonella serotypes. Antibiotics resistance profiles of Salmonella serotypes were not statistically associated with blaCTX-M-1 and int1 resistance genes (p > 0.05). S. Typhimurium and other Salmonella serotypes did not show significantly different antibiotic susceptibility to the tested antibiotics (p = 0.536). According to the results, there is a high prevalence of resistance to cephalosporin compounds among Salmonella spp. and S. Typhimurium in Zabol, Iran.